Acute Promyelitic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcr...

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Bibliographic Details
Other Authors: Pandolfi, Pier Paolo (Editor), Vogt, Peter K. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 2007, 2007
Edition:1st ed. 2007
Series:Current Topics in Microbiology and Immunology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Description
Summary:Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy
Physical Description:VIII, 274 p. 16 illus., 9 illus. in color online resource
ISBN:9783540345947