Mammalian Alkaline Phosphatases From Biology to Applications in Medicine and Biotechnology

A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: -- * The structure, regulation and expression of the AP genes -- * The three-dimensional structure of APs and mutagenesis work that further define...

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Bibliographic Details
Main Author: Millán, José Luis
Format: eBook
Language:English
Published: Weinheim Wiley-Vch 2006, ©2006
Subjects:
Online Access:
Collection: Wiley Online Books - Collection details see MPG.ReNa
Description
Summary:A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: -- * The structure, regulation and expression of the AP genes -- * The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes -- * The phenotypic abnormalities of the different AP knockout mice -- * Our current understanding of the in vivo role of the AP isozymes. -- The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.
Physical Description:XV,322 Seiten
ISBN:9783527608065