Mammalian Alkaline Phosphatases From Biology to Applications in Medicine and Biotechnology
A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: -- * The structure, regulation and expression of the AP genes -- * The three-dimensional structure of APs and mutagenesis work that further define...
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Format: | eBook |
Language: | English |
Published: |
Weinheim
Wiley-Vch
2006, ©2006
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Online Access: | |
Collection: | Wiley Online Books - Collection details see MPG.ReNa |
Summary: | A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: -- * The structure, regulation and expression of the AP genes -- * The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes -- * The phenotypic abnormalities of the different AP knockout mice -- * Our current understanding of the in vivo role of the AP isozymes. -- The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology. |
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Physical Description: | XV,322 Seiten |
ISBN: | 9783527608065 |