Anaplastic lymphoma kinase inhibitors for genetically rearranged non-small cell lung cancer a review of the clinical effectiveness

With all the anaplastic lymphoma kinase inhibitors (ALKIs) available in the market, it is important to understand the comparative clinical effectiveness and safety profile of the different ALKIs in relation to each other, particularly in the first-line and second-line setting. This report was undert...

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Bibliographic Details
Main Authors: Islam, Saadul, Argáez, Charlene (Author)
Corporate Author: Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: Ottawa (ON) Canadian Agency for Drugs and Technologies in Health 2018, November 1, 2018
Edition:Version 1.0
Series:CADTH rapid response report: summary with critical appraisal
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:With all the anaplastic lymphoma kinase inhibitors (ALKIs) available in the market, it is important to understand the comparative clinical effectiveness and safety profile of the different ALKIs in relation to each other, particularly in the first-line and second-line setting. This report was undertaken to examine the current evidence surrounding the comparative clinical benefits of first-line ALKIs among patients naive to previous anaplastic lymphoma kinase (ALK) treatment (ALK-naive), and second-line ALKIs among patients who have been pretreated with other ALKIs and had disease progression (ALK-pretreated)
Physical Description:1 PDF file (32 pages) illustrations