Methods for assessing the adherence to medical devices

Assessing patient adherence to medication is necessary to distinguish between nonadherence and inferior drug efficacy, which is crucial to avoid poor clinical outcomes. Adherence measurements pose various challenges, because many methods rely on subjective assessments or slow and costly measurements...

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Bibliographic Details
Main Authors: Johnson, Leah M., Swarner, Stephanie L. (Author), Straten, Ariane van der (Author), Rothrock, Ginger D. (Author)
Corporate Author: RTI International
Format: eBook
Language:English
Published: Research Triangle Park, NC RTI Press 2016, October 2016
Series:RTI press methods report
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:Assessing patient adherence to medication is necessary to distinguish between nonadherence and inferior drug efficacy, which is crucial to avoid poor clinical outcomes. Adherence measurements pose various challenges, because many methods rely on subjective assessments or slow and costly measurements, which are infeasible in resource-poor settings. Recent developments of new medical devices for delivery of medications requires additional considerations in adherence. In this report, we propose that medical devices may serve a dual-functional purpose: to deliver the drug(s) and monitor adherence. We provide an illustrative case study that involves assessing the adherence of vaginal rings for delivery of antiretroviral drugs for pre-exposure prophylaxis (PrEP) of HIV.
Item Description:"RTI Press publication MR-0036-1610."
Physical Description:1 PDF file (ii, 10 pages) illustrations