Colistin for prophylactic use in non-cystic fibrosis bronchiectasis or COPD with exacerbations a review of clinical and cost-effectiveness and guidelines

Chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema, is a leading cause of morbidity and mortality in Canada, with a national estimate of COPD prevalence of approximately 4% in 2011. Patients with COPD can experience exacerbations, or periods of worsening of...

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Bibliographic Details
Main Authors: Ho, Chuong, Severn, Melissa (Author)
Corporate Author: Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: Ottawa CADTH 2017, June 27, 2017
Series:CADTH rapid response report: summary with critical appraisal
Subjects:
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Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:Chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema, is a leading cause of morbidity and mortality in Canada, with a national estimate of COPD prevalence of approximately 4% in 2011. Patients with COPD can experience exacerbations, or periods of worsening of COPD symptoms such as increased breathlessness, tiredness, fever and change in sputum colour. Bronchiectasis, or dilatation of the airways due to infective causes or cystic fibrosis (CF), had an incidence of 272 per 100 000 in those over 75 years of age in the US as of 2005. The reduced ability to clear secretions from dilated airways eventually leads to airway blockage and loss of lung function
Physical Description:1 PDF file (13 pages) illustrations